print_label | resize_label

Frequently Asked Questions

icon one What is OIC?

“OIC” stands for “opioid-induced constipation,” which is a different type of constipation caused by opioids. Opioids are prescription medicines like codeine, hydrocodone, morphine, oxycodone, fentanyl, and tramadol that are used to treat pain.

OIC is one of the most common side effects of opioids. It can happen when someone starts taking prescription opioids and can last as long as they’re taking them.

Learn more about OIC >

icon one How do opioids cause OIC?

Opioids block pain signals by attaching to something called mu-receptors in the brain and other parts of the central nervous system. But opioids also attach to mu-receptors in the bowel, which can cause OIC.

Learn more about OIC >

icon one What is MOVANTIK and who is it for?

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

icon one How does MOVANTIK work for OIC?

MOVANTIK one pill once a day is specifically designed for OIC in adults with chronic non-cancer pain. It works by blocking opioids from binding to something called mu-receptors in your bowel.

Learn more about MOVANTIK >

icon one How fast does MOVANTIK work?

In clinical studies, MOVANTIK worked quickly, often within 6 to 12 hours of the first dose.

Learn more about MOVANTIK >

icon one Does MOVANTIK have the same approved use as OTC laxatives?

Over-the-counter laxatives are labeled for occasional constipation. MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

Learn more about MOVANTIK >

icon one Will taking MOVANTIK change the way I take my opioid pain meds?

When starting MOVANTIK, changes to your opioid dosing regimen are not required. It’s important to talk to your doctor about your pain management and opioid dose.

icon one What are the possible side effects of MOVANTIK?

MOVANTIK may cause serious side effects, including:

  • Opioid withdrawal. You may have symptoms of opioid withdrawal during treatment with MOVANTIK including sweating, chills, diarrhea, stomach pain, anxiety, irritability, and yawning. If you take methadone to treat your pain, you may be more likely to have stomach pain and diarrhea than people who do not take methadone. Tell your health care provider if you have any of these symptoms

  • Severe stomach pain or diarrhea, or both severe stomach pain and diarrhea. Severe stomach pain and diarrhea can happen when you take MOVANTIK. These problems can happen within a few days after you start taking MOVANTIK and can lead to hospitalization. Stop taking MOVANTIK and call your healthcare provider right away if you have severe stomach pain or diarrhea, or both severe stomach pain and diarrhea

  • Tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you have stomach pain that gets worse or does not go away, stop taking MOVANTIK and get emergency medical help right away

The most common side effects of MOVANTIK include: stomach (abdomen) pain, diarrhea, nausea, gas, vomiting, and headache.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of MOVANTIK.

Call your doctor for medical advice about side effects. You may report side effects related to AstraZeneca products by clicking here. 

Please see Important Safety Information and Medication Guide and US Full Prescribing Information.

Learn more about Possible Side Effects >

icon one How should I take MOVANTIK?

You should take MOVANTIK exactly as your health care provider tells you. Be sure to take your prescribed dose of MOVANTIK one time each day, on an empty stomach, at least 1 hour before your first meal of the day or 2 hours after the meal. You should also stop taking other laxatives before you start treatment with MOVANTIK. Your health care provider may prescribe other laxatives if MOVANTIK does not work after 3 days of treatment.

Learn more about taking MOVANTIK >

icon one Is MOVANTIK covered by insurance?

The majority of commercial patients* nationwide are covered for MOVANTIK. Ask your pharmacist or check with your insurance provider.

*”Patients” means covered lives (Commercial, Commercial [BCBS], Employer, Federal Employees Health Benefit Plans [FEHBPs], Federal Programs, Municipal Plan, Pharmacy Benefit Manager [PBM], Union) at Tiers 1-7 and the $0 Co-pay tier in the region, as calculated by Fingertip Formulary® as of December xx, xxxx.

”Covered” means any coverage level, specifically Tiers 1-7 and the $0 Co-pay tier, regardless of restrictions.

icon one How much does MOVANTIK cost?

With the MOVANTIK Savings Card, eligible patients pay as little as $0 per month,* a cost less than OTC laxatives.†‡

*Subject to eligibility. Restrictions apply. See home page of this website for eligibility information and instructions. If eligible, show your card and prescription to your pharmacist for instant savings.

OTC laxatives include Colace®, Dulcolax®, ex-lax®, MiraLAX®, Peri-Colace®, Senokot®, and Senokot-S®.

Pricing comparisons do not imply comparable efficacy, safety, or FDA-approved indications.

Learn more about MOVANTIK Savings Card >

IMPORTANT SAFETY INFORMATION ABOUT MOVANTIK

IMPORTANT SAFETY INFORMATION ABOUT MOVANTIK

  • MOVANTIK may cause serious side effects, including:
    • Opioid withdrawal. You may have symptoms of opioid withdrawal during treatment with MOVANTIK, including sweating, chills, diarrhea, stomach pain, anxiety, irritability, and yawning. Patients taking methadone to treat their pain may be more likely to experience stomach pain and diarrhea. Tell your doctor if you have any of these symptoms
    • Severe Stomach Pain and/or Diarrhea. This can happen within a few days of starting MOVANTIK and can lead to hospitalization. If either of these side effects occurs, stop taking MOVANTIK and call your doctor immediately
    • Tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that gets worse or does not go away, stop taking MOVANTIK and get emergency medical help right away
  • Do not take MOVANTIK if you:
    • Have a bowel blockage (intestinal obstruction) or have a history of bowel blockage
    • Are allergic to MOVANTIK or any of the ingredients in MOVANTIK
  • MOVANTIK can interact with other medicines and cause side effects, including opioid withdrawal symptoms (see symptoms above). Tell your doctor or pharmacist before you start or stop any medicines during treatment with MOVANTIK
  • Before you take MOVANTIK, tell your doctor about all of your medical conditions, including if you:
    • have any stomach, bowel (intestines), kidney, or liver problems
    • are pregnant or plan to become pregnant. Taking MOVANTIK during pregnancy may cause opioid withdrawal symptoms in you or your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with MOVANTIK
    • are breastfeeding or plan to breastfeed. It is not known if MOVANTIK passes into your breast milk. Taking MOVANTIK while you are breastfeeding may cause opioid withdrawal in your baby. You and your healthcare provider should decide if you will take MOVANTIK or breastfeed. You should not breastfeed if you take MOVANTIK
  • Tell your healthcare provider if you are pregnant or plan to become pregnant during treatment with MOVANTIK
  • Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect the way MOVANTIK works
  • If you stop taking your opioid pain medicine, stop taking MOVANTIK and tell your doctor
  • Avoid eating grapefruit or drinking grapefruit juice during treatment with MOVANTIK
  • The most common side effects of MOVANTIK include: Stomach (abdomen) pain, diarrhea, nausea, gas, vomiting, headache, and excessive sweating

APPROVED USE FOR MOVANTIK

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

MOVANTIK is a prescription medicine used to treat constipation caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain not caused by active cancer.

Click here for the Medication GuideMedication Guide and full Prescribing InformationPrescribing Information for MOVANTIK.

You are now leaving this web site

close-icon

You will be taken to a telehealth site to speak with a doctor online. CONTINUE This site is maintained by a third party who is solely responsible for its content. AstraZeneca is not responsible for the Privacy Policy of any third party Web sites. We encourage you to read the Privacy Policy of every Web site you visit.

 
 

AZ & me